Researchers for the first time formed a full-fledged human embryo from single skin cells.
To study congenital diseases, problems of infertility, the effect of toxins and viruses on the fetus, scientists use embryos at an early stage of development. However, their work is severely limited due to a lack of suitable material, as well as a number of legal and ethical barriers. Now a team from Monash University has developed a technology for creating full-fledged artificial versions of blastocysts.
To do this, Australian researchers altered the expression of genes in skin cells by reprogramming their nuclei so that they behave like the building blocks of a blastocyst. Then they placed them in a jelly-like framework, where the modified cells self-organized into the required structure..
Artificial early embryos are not identical to natural ones, since they lack an outer membrane and develop developmental disorders after a few days. These properties, in combination with all other structural similarities, make them a suitable material for conducting research without guidelines..
The technology will make it easier for scientists to access early human embryos, which will accelerate the study of various developmental issues.
Scientists have created an early human embryo from skin cells
We also previously reported on the development of a ceramic 3D printer ink that allows for the printing of artificial bones. right inside the body.
text: Ilya Bauer, photo: Monash University